Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM39937
Substrate
n/a
Meas. Tech.
Estrogen Receptor (alpha) binding: Dose Response of Primary Screen Assay
EC50
1.41±n/a nM
Citation
 PubChem, PC Estrogen Receptor (alpha) binding: Dose Response of Primary Screen Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM39937
Synonyms:
2-[2-(5-bromanylfuran-2-yl)-3H-benzimidazol-5-yl]isoindole-1,3-dione | 2-[2-(5-bromo-2-furanyl)-3H-benzimidazol-5-yl]isoindole-1,3-dione | 2-[2-(5-bromo-2-furyl)-3H-benzimidazol-5-yl]isoindoline-1,3-quinone | 2-[2-(5-bromofuran-2-yl)-3H-benzimidazol-5-yl]isoindole-1,3-dione | MLS000041619 | SMR000046410 | cid_665299
Type:
Small organic molecule
Emp. Form.:
C19H10BrN3O3
Mol. Mass.:
408.205
SMILES:
Brc1ccc(o1)-c1nc2ccc(cc2[nH]1)N1C(=O)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: