Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM42087
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors
EC50
670±1180 nM
Citation
 PubChem, PC Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM42087
Synonyms:
7-[3-(dimethylamino)propylamino]-2-methyl-14H-naphtho[3,2-a]phenoxazine-8,13-dione | 7-[3-(dimethylamino)propylamino]-2-methyl-14H-naphtho[3,2-a]phenoxazine-8,13-quinone | BIM-0020537.P001 | cid_2847109
Type:
Small organic molecule
Emp. Form.:
C26H25N3O3
Mol. Mass.:
427.495
SMILES:
CN(C)CCCNc1cc2oc3ccc(C)cc3nc2c2c(O)c3ccccc3c(=O)c12
Structure:
Search PDB for entries with ligand similarity: