Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42445
Substrate
n/a
Meas. Tech.
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
IC50
30390±n/a nM
Citation
 PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42445
Synonyms:
5-tert-butyl-N-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2-methoxyphenyl)-3-methyl-2-furamide | 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-(2-methoxyphenyl)-3-methyl-furan-2-carboxamide | 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-methoxyphenyl)-3-methyl-2-furancarboxamide | 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-methoxyphenyl)-3-methylfuran-2-carboxamide | MLS000764944 | SMR000286749 | cid_1454987
Type:
Small organic molecule
Emp. Form.:
C24H32N2O4
Mol. Mass.:
412.5219
SMILES:
COc1ccccc1N(CC(=O)NC1CCCC1)C(=O)c1oc(cc1C)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: