Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43246
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
665.4±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43246
Synonyms:
2-(2,5-dimethyl-3-furoyl)oxybenzoic acid | 2-(2,5-dimethylfuran-3-carbonyl)oxybenzoic acid | 2-(2,5-dimethylfuran-3-yl)carbonyloxybenzoic acid | 2-[(2,5-dimethyl-3-furanyl)-oxomethoxy]benzoic acid | 2-[(2,5-dimethyl-3-furoyl)oxy]benzoic acid | MLS000062122 | SMR000070396 | cid_877366
Type:
Small organic molecule
Emp. Form.:
C14H12O5
Mol. Mass.:
260.2421
SMILES:
Cc1cc(C(=O)Oc2ccccc2C(O)=O)c(C)o1
Structure:
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