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Target
RAC-alpha serine/threonine-protein kinase
Ligand
BDBM32360
Substrate
n/a
Meas. Tech.
AKT counterscreen of confirmed PKD inhibitors-57K library
IC50
>100000±n/a nM
Citation
 PubChem, PC AKT counterscreen of confirmed PKD inhibitors-57K library PubChem Bioassay (2008)[AID] 
Target
Name:
RAC-alpha serine/threonine-protein kinase
Synonyms:
AKT phosphorylation (p-AKT) | AKT1 | AKT1/PPP1CA | AKT1_HUMAN | C-AKT | PKB | PKB alpha | Protein kinase Akt-1 | Protein kinase B | Protein kinase B (AKT1) | Protein kinase B (Akt 1) | Protein kinase B (Akt) | Protein kinase B alpha | Protein kinase B alpha (AKT1) | Proto-oncogene Akt (Akt1) | Proto-oncogene c-Akt (AKT) | Proto-oncogene c-Akt (AKT1) | RAC | RAC-PK-alpha | RAC-alpha serine/threonine-protein kinase (AKT) | RAC-alpha serine/threonine-protein kinase (AKT1) | RAC-alpha serine/threonine-protein kinase (pAKT)
Type:
Enzyme
Mol. Mass.:
55681.25
Organism:
Homo sapiens (Human)
Description:
P31749
Residue:
480
Sequence:
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
  
Inhibitor
Name:
BDBM32360
Synonyms:
(3,5-dichloro-2-pyridyl)-[1-(2-pyridyl)ethylideneamino]amine | 3,5-bis(chloranyl)-N-(1-pyridin-2-ylethylideneamino)pyridin-2-amine | 3,5-dichloro-N-(1-pyridin-2-ylethylideneamino)pyridin-2-amine | 3,5-dichloro-N-[1-(2-pyridinyl)ethylideneamino]-2-pyridinamine | MLS000772548 | SMR000377273 | cid_3351416
Type:
Small organic molecule
Emp. Form.:
C12H10Cl2N4
Mol. Mass.:
281.141
SMILES:
CC(N=Nc1ncc(Cl)cc1Cl)c1ccccn1 |w:3.3|
Structure:
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