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Target
Cyclin-dependent kinase 7
Ligand
BDBM32354
Substrate
n/a
Meas. Tech.
CDK7 counterscreen of confirmed PKD inhibitors-57K library addition
IC50
>100000±n/a nM
Citation
 PubChem, PC CDK7 counterscreen of confirmed PKD inhibitors-57K library addition PubChem Bioassay (2008)[AID] 
Target
Name:
Cyclin-dependent kinase 7
Synonyms:
39 kDa protein kinase | CAK | CAK1 | CDK-activating kinase | CDK-activating kinase 1 (CAK) | CDK7 | CDK7_HUMAN | CDKN7 | Cell division protein kinase 7 | Cyclin-Dependent Kinase 7 (CDK7) | Cyclin-dependent kinase 7 (CDK7/cyclin H) | MO15 | P39 Mo15 | STK1 | TFIIH basal transcription factor complex kinase subunit
Type:
Enzyme Subunit
Mol. Mass.:
39047.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
346
Sequence:
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
  
Inhibitor
Name:
BDBM32354
Synonyms:
4-(cyclohexanecarbonyl)-1H-pyrrole-2-carboxylic acid | 4-(cyclohexylcarbonyl)-1H-pyrrole-2-carboxylic acid | 4-[cyclohexyl(oxo)methyl]-1H-pyrrole-2-carboxylic acid | 4-cyclohexylcarbonyl-1H-pyrrole-2-carboxylic acid | MLS000736313 | SMR000338263 | cid_1482736
Type:
Small organic molecule
Emp. Form.:
C12H15NO3
Mol. Mass.:
221.2524
SMILES:
OC(=O)c1cc(c[nH]1)C(=O)C1CCCCC1
Structure:
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