Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43545
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
9778±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43545
Synonyms:
(3-Cyano-indol-1-yl)-acetic acid | 2-(3-cyano-1-indolyl)acetic acid | 2-(3-cyanoindol-1-yl)acetic acid | 2-(3-cyanoindol-1-yl)ethanoic acid | MLS000032236 | SMR000013848 | cid_652683
Type:
Small organic molecule
Emp. Form.:
C11H8N2O2
Mol. Mass.:
200.1934
SMILES:
OC(=O)Cn1cc(C#N)c2ccccc12
Structure:
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