Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43573
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
5674±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43573
Synonyms:
6-({[4-(3,4-dihydro-1(2H)-quinolinylsulfonyl)phenyl]amino}carbonyl)-3-cyclohexene-1-carboxylic acid | 6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)anilino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid | 6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid | MLS000051782 | SMR000080802 | cid_2971528
Type:
Small organic molecule
Emp. Form.:
C23H24N2O5S
Mol. Mass.:
440.512
SMILES:
OC(=O)C1CC=CCC1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCc2ccccc12 |c:5|
Structure:
Search PDB for entries with ligand similarity: