Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43578
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
8513±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43578
Synonyms:
3-(5-bromanylfuran-2-yl)-5-(5-chloranyl-2-methoxy-phenyl)-1,2,4-oxadiazole | 3-(5-bromo-2-furanyl)-5-(5-chloro-2-methoxyphenyl)-1,2,4-oxadiazole | 3-(5-bromo-2-furyl)-5-(5-chloro-2-methoxy-phenyl)-1,2,4-oxadiazole | 3-(5-bromofuran-2-yl)-5-(5-chloro-2-methoxyphenyl)-1,2,4-oxadiazole | MLS000119204 | SMR000096132 | cid_1517735
Type:
Small organic molecule
Emp. Form.:
C13H8BrClN2O3
Mol. Mass.:
355.571
SMILES:
COc1ccc(Cl)cc1-c1nc(no1)-c1ccc(Br)o1
Structure:
Search PDB for entries with ligand similarity: