Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43631
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43631
Synonyms:
2-(2-methoxyethylsulfanyl)-N-(2-phenylethyl)benzamide | 2-(2-methoxyethylthio)-N-(2-phenylethyl)benzamide | 2-(2-methoxyethylthio)-N-phenethyl-benzamide | 2-[(2-methoxyethyl)thio]-N-(2-phenylethyl)benzamide | MLS000675444 | SMR000295168 | cid_2218462
Type:
Small organic molecule
Emp. Form.:
C18H21NO2S
Mol. Mass.:
315.43
SMILES:
COCCSc1ccccc1C(=O)NCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: