Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43639
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
644±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43639
Synonyms:
2-[1-(4-ethoxybenzyl)-4-(1H-indol-2-ylmethyl)piperazin-2-yl]ethanol | 2-[1-[(4-ethoxyphenyl)methyl]-4-(1H-indol-2-ylmethyl)-2-piperazinyl]ethanol | 2-[1-[(4-ethoxyphenyl)methyl]-4-(1H-indol-2-ylmethyl)piperazin-2-yl]ethanol | MLS000733946 | SMR000317157 | cid_16191831
Type:
Small organic molecule
Emp. Form.:
C24H31N3O2
Mol. Mass.:
393.5218
SMILES:
CCOc1ccc(CN2CCN(Cc3cc4ccccc4[nH]3)CC2CCO)cc1
Structure:
Search PDB for entries with ligand similarity: