Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43673
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43673
Synonyms:
MLS000065628 | N-[2-(1-cyclohexen-1-yl)ethyl]-2,5-dimethyl-3-furamide | N-[2-(1-cyclohexenyl)ethyl]-2,5-dimethyl-3-furancarboxamide | N-[2-(cyclohexen-1-yl)ethyl]-2,5-dimethyl-3-furamide | N-[2-(cyclohexen-1-yl)ethyl]-2,5-dimethyl-furan-3-carboxamide | N-[2-(cyclohexen-1-yl)ethyl]-2,5-dimethylfuran-3-carboxamide | SMR000080267 | cid_2712666
Type:
Small organic molecule
Emp. Form.:
C15H21NO2
Mol. Mass.:
247.3327
SMILES:
Cc1cc(C(=O)NCCC2=CCCCC2)c(C)o1 |t:9|
Structure:
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