Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43684
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43684
Synonyms:
2-Amino-benzoic acid 2-(2,3-dihydro-indol-1-yl)-2-oxo-ethyl ester | 2-aminobenzoic acid (2-indolin-1-yl-2-keto-ethyl) ester | 2-aminobenzoic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester | MLS000528743 | SMR000121218 | [2-(2,3-dihydroindol-1-yl)-2-oxidanylidene-ethyl] 2-azanylbenzoate | [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] 2-aminobenzoate | cid_1089231
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3
Mol. Mass.:
296.3205
SMILES:
Nc1ccccc1C(=O)OCC(=O)N1CCc2ccccc12
Structure:
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