Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43695
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43695
Synonyms:
(E)-1-(5-methyl-2-furanyl)-3-(3-nitroanilino)-2-propen-1-one | (E)-1-(5-methyl-2-furyl)-3-(3-nitroanilino)prop-2-en-1-one | (E)-1-(5-methylfuran-2-yl)-3-(3-nitroanilino)prop-2-en-1-one | (E)-1-(5-methylfuran-2-yl)-3-[(3-nitrophenyl)amino]prop-2-en-1-one | 1-(5-methyl-2-furyl)-3-[(3-nitrophenyl)amino]-2-propen-1-one | MLS000579249 | SMR000198529 | cid_2192119
Type:
Small organic molecule
Emp. Form.:
C14H12N2O4
Mol. Mass.:
272.2561
SMILES:
Cc1ccc(o1)C(=O)CC=Nc1cccc(c1)[N+]([O-])=O |w:10.11|
Structure:
Search PDB for entries with ligand similarity: