Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43701
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43701
Synonyms:
(5-Methyl-4-nitro-2H-pyrazol-3-yl)-m-tolyl-amine | (5-methyl-4-nitro-1H-pyrazol-3-yl)-(m-tolyl)amine | 5-methyl-N-(3-methylphenyl)-4-nitro-1H-pyrazol-3-amine | MLS000569061 | SMR000176283 | cid_3122354
Type:
Small organic molecule
Emp. Form.:
C11H12N4O2
Mol. Mass.:
232.2386
SMILES:
Cc1n[nH]c(Nc2cccc(C)c2)c1[N+]([O-])=O
Structure:
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