Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43715
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Human
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43715
Synonyms:
MLS000701139 | SMR000226438 | [3-amino-4-(dimethylamino)-2-thieno[2,3-b]pyridinyl]-phenylmethanone | [3-amino-4-(dimethylamino)thieno[2,3-b]pyridin-2-yl](phenyl)methanone | [3-amino-4-(dimethylamino)thieno[2,3-b]pyridin-2-yl]-phenyl-methanone | [3-amino-4-(dimethylamino)thieno[2,3-b]pyridin-2-yl]-phenylmethanone | [3-azanyl-4-(dimethylamino)thieno[2,3-b]pyridin-2-yl]-phenyl-methanone | cid_794365
Type:
Small organic molecule
Emp. Form.:
C16H15N3OS
Mol. Mass.:
297.375
SMILES:
CN(C)c1ccnc2sc(C(=O)c3ccccc3)c(N)c12
Structure:
Search PDB for entries with ligand similarity: