Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43727
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43727
Synonyms:
2-(4-ethylanilino)-7-methyl-7,8-dihydro-6H-quinazolin-5-one | 2-[(4-ethylphenyl)amino]-7-methyl-7,8-dihydro-6H-quinazolin-5-one | MLS000718780 | SMR000291048 | cid_2986465
Type:
Small organic molecule
Emp. Form.:
C17H19N3O
Mol. Mass.:
281.3523
SMILES:
CCc1ccc(Nc2ncc3C(=O)CC(C)Cc3n2)cc1
Structure:
Search PDB for entries with ligand similarity: