Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43732
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43732
Synonyms:
1-(4-tert-butylphenyl)-3-(3-methoxyphenyl)urea | MLS000624887 | N-(4-tert-butylphenyl)-N'-(3-methoxyphenyl)urea | SMR000293650 | cid_727830
Type:
Small organic molecule
Emp. Form.:
C18H22N2O2
Mol. Mass.:
298.3795
SMILES:
COc1cccc(NC(=O)Nc2ccc(cc2)C(C)(C)C)c1
Structure:
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