Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43733
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43733
Synonyms:
5-(4-nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide | 5-(4-nitrophenyl)-N-(2-thiazolyl)-2-furancarboxamide | 5-(4-nitrophenyl)-N-1,3-thiazol-2-yl-2-furamide | 5-(4-nitrophenyl)-N-thiazol-2-yl-2-furamide | MLS000662245 | SMR000293139 | cid_975008
Type:
Small organic molecule
Emp. Form.:
C14H9N3O4S
Mol. Mass.:
315.304
SMILES:
[O-][N+](=O)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1nccs1
Structure:
Search PDB for entries with ligand similarity: