Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43747
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43747
Synonyms:
4-methyl-7-(2-oxidanylidenepropoxy)-3-phenyl-chromen-2-one | 4-methyl-7-(2-oxopropoxy)-3-phenyl-1-benzopyran-2-one | 4-methyl-7-(2-oxopropoxy)-3-phenylchromen-2-one | 7-acetonyloxy-4-methyl-3-phenyl-coumarin | MLS000624407 | SMR000323718 | cid_7198312
Type:
Small organic molecule
Emp. Form.:
C19H16O4
Mol. Mass.:
308.3279
SMILES:
CC(=O)COc1ccc2c(C)c(-c3ccccc3)c(=O)oc2c1
Structure:
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