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Target
Tumor necrosis factor ligand superfamily member 10
Ligand
BDBM44375
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that potentiate TRAIL-induced apoptosis in PPC-1 cells.
IC50
>10000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that potentiate TRAIL-induced apoptosis in PPC-1 cells. PubChem Bioassay (2009)[AID] 
Target
Name:
Tumor necrosis factor ligand superfamily member 10
Synonyms:
APO2L | TNF10_HUMAN | TNFSF10 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10
Type:
PROTEIN
Mol. Mass.:
32511.55
Organism:
Homo sapiens (Human)
Description:
EBI_101343
Residue:
281
Sequence:
MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
  
Inhibitor
Name:
BDBM44375
Synonyms:
MLS-0390927.0001 | [2-(4-methylsulfanyl-6-phenyl-1,3,5-triazin-2-yl)phenyl] acetate | [2-(4-methylsulfanyl-6-phenyl-1,3,5-triazin-2-yl)phenyl] ethanoate | acetic acid [2-[4-(methylthio)-6-phenyl-1,3,5-triazin-2-yl]phenyl] ester | acetic acid [2-[4-(methylthio)-6-phenyl-s-triazin-2-yl]phenyl] ester | cid_679790
Type:
Small organic molecule
Emp. Form.:
C18H15N3O2S
Mol. Mass.:
337.396
SMILES:
CSc1nc(nc(n1)-c1ccccc1OC(C)=O)-c1ccccc1
Structure:
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