Reaction Details Report a problem with these data
Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM41242
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM41242
Synonyms:
MLS000047147 | N-[1-[(4-methoxyphenyl)methylamino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide | N-[1-[(4-methoxyphenyl)methylamino]-1-oxopropan-2-yl]-1-benzofuran-2-carboxamide | N-[1-[(4-methoxyphenyl)methylamino]-1-oxopropan-2-yl]-2-benzofurancarboxamide | N-[2-keto-1-methyl-2-(p-anisylamino)ethyl]coumarilamide | N-{2-[(4-methoxybenzyl)amino]-1-methyl-2-oxoethyl}-1-benzofuran-2-carboxamide | SMR000033158 | cid_3241239
Type:
Small organic molecule
Emp. Form.:
C20H20N2O4
Mol. Mass.:
352.3838
SMILES:
COc1ccc(CNC(=O)C(C)NC(=O)c2cc3ccccc3o2)cc1
Structure:
Search PDB for entries with ligand similarity: