Reaction Details Report a problem with these data
Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM41417
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM41417
Synonyms:
MLS000116423 | N-(5-methyl-2-phenyl-3-pyrazolyl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | N-(5-methyl-2-phenyl-pyrazol-3-yl)-4,5-dihydrobenz[g]indoxazene-3-carboxamide | N-(5-methyl-2-phenyl-pyrazol-3-yl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | N-(5-methyl-2-phenylpyrazol-3-yl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | SMR000093400 | cid_5309067
Type:
Small organic molecule
Emp. Form.:
C22H18N4O2
Mol. Mass.:
370.4039
SMILES:
Cc1cc(NC(=O)c2noc-3c2CCc2ccccc-32)n(n1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: