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Target
Ephrin type-A receptor 4
Ligand
BDBM44526
Substrate
n/a
Meas. Tech.
Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists
IC50
10800±n/a nM
Citation
 PubChem, PC Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists PubChem Bioassay (2008)[AID] 
Target
Name:
Ephrin type-A receptor 4
Synonyms:
EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
109812.17
Organism:
Mus musculus
Description:
gi_34328113
Residue:
986
Sequence:
MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV
  
Inhibitor
Name:
BDBM44526
Synonyms:
(4-nitrophenyl)-diphenyl-amine | (4-nitrophenyl)diphenylamine | 4-nitro-N,N-diphenyl-aniline | 4-nitro-N,N-diphenylaniline | MLS000577562 | SMR000185555 | cid_350141
Type:
Small organic molecule
Emp. Form.:
C18H14N2O2
Mol. Mass.:
290.316
SMILES:
[O-][N+](=O)c1ccc(cc1)N(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: