Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44534
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44534
Synonyms:
1-(4-Bromo-phenyl)-2-(2,3-dihydro-benzo[d]imidazo[1,2-a]imidazol-9-yl)-ethanone | 1-(4-bromophenyl)-2-(1,2-dihydroimidazo[1,2-a]benzimidazol-4-yl)ethanone;hydrobromide | MLS000070324 | SMR000009469 | cid_6603329
Type:
Small organic molecule
Emp. Form.:
C17H14BrN3O
Mol. Mass.:
356.217
SMILES:
Brc1ccc(cc1)C(=O)CN1C2=NCCN2c2ccccc12 |t:12|
Structure:
Search PDB for entries with ligand similarity: