Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44545
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44545
Synonyms:
(6-chloranyl-2-phenyl-chromen-4-ylidene)-(2-methylpropyl)azanium;tetrafluoroborate | (6-chloro-2-phenyl-1-benzopyran-4-ylidene)-(2-methylpropyl)ammonium;tetrafluoroborate | (6-chloro-2-phenyl-chromen-4-ylidene)-isobutyl-ammonium;tetrafluoroborate | (6-chloro-2-phenylchromen-4-ylidene)-(2-methylpropyl)azanium;tetrafluoroborate | MLS000519375 | SMR000129794 | cid_9551073
Type:
Small organic molecule
Emp. Form.:
C19H19ClNO
Mol. Mass.:
312.813
SMILES:
CC(C)C\[NH+]=c1/cc(oc2ccc(Cl)cc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: