Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44546
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44546
Synonyms:
MLS000556387 | N',N'-diethyl-N-(8-methoxy-3,4-dihydropyrazino[1,2-a]indol-1-yl)ethane-1,2-diamine;hydrochloride | N,N-Diethyl-N'-(8-methoxy-3,4-dihydro-pyrazino[1,2-a]indol-1-yl)-ethane-1,2-diamine | SMR000147704 | cid_9551666 | diethyl-[2-[(8-methoxy-3,4-dihydropyrazin[1,2-a]indol-1-yl)amino]ethyl]amine;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C18H26N4O
Mol. Mass.:
314.4252
SMILES:
CCN(CC)CCN=C1NCCn2c1cc1cc(OC)ccc21 |w:7.6|
Structure:
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