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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41634
Substrate
n/a
Meas. Tech.
Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
IC50
>40000±n/a nM
Citation
 PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay (2008)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41634
Synonyms:
4-morpholinyl-[3-phenyl-6-(trifluoromethyl)-2-thieno[3,2-b]pyridinyl]methanone | SR-01000759132-1 | cid_3613860 | morpholin-4-yl-[3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]methanone | morpholino-[3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]methanone
Type:
Small organic molecule
Emp. Form.:
C19H15F3N2O2S
Mol. Mass.:
392.395
SMILES:
FC(F)(F)c1cnc2c(c(sc2c1)C(=O)N1CCOCC1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: