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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM33123
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
5530±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM33123
Synonyms:
MLS000587395 | N-[(2-benzoxy-5-bromo-benzylidene)amino]-2-[[2-(3-methylphenoxy)acetyl]amino]acetamide | N-[(5-bromanyl-2-phenylmethoxy-phenyl)methylideneamino]-2-[2-(3-methylphenoxy)ethanoylamino]ethanamide | N-[(5-bromo-2-phenylmethoxyphenyl)methylideneamino]-2-[[2-(3-methylphenoxy)-1-oxoethyl]amino]acetamide | N-[(5-bromo-2-phenylmethoxyphenyl)methylideneamino]-2-[[2-(3-methylphenoxy)acetyl]amino]acetamide | N-[1-(2-Benzyloxy-5-bromo-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-2-m-tolyloxy-acetamide | SMR000211373 | cid_1908777
Type:
Small organic molecule
Emp. Form.:
C25H24BrN3O4
Mol. Mass.:
510.38
SMILES:
Cc1cccc(OCC(=O)NCC(=O)NN=Cc2cc(Br)ccc2OCc2ccccc2)c1 |w:15.14|
Structure:
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