Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46325
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
5168±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46325
Synonyms:
4-[benzyl(mesyl)amino]-N-[(4-isopropoxybenzylidene)amino]benzamide | 4-[benzyl(methylsulfonyl)amino]-N-[(4-propan-2-yloxyphenyl)methylideneamino]benzamide | 4-[methylsulfonyl-(phenylmethyl)amino]-N-[(4-propan-2-yloxyphenyl)methylideneamino]benzamide | MLS000547665 | N-Benzyl-N-[4-(4-isopropoxy-benzylidene-hydrazinocarbonyl)-phenyl]-methanesulfonamide | SMR000171733 | cid_1107784
Type:
Small organic molecule
Emp. Form.:
C25H27N3O4S
Mol. Mass.:
465.565
SMILES:
CC(C)Oc1ccc(C=NNC(=O)c2ccc(cc2)N(Cc2ccccc2)S(C)(=O)=O)cc1 |w:9.9|
Structure:
Search PDB for entries with ligand similarity: