Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM37028
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
4010±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM37028
Synonyms:
MLS000098514 | N-[4-(5-chloranylthiophen-2-yl)-1,3-thiazol-2-yl]pyridine-4-carboxamide | N-[4-(5-chloro-2-thienyl)thiazol-2-yl]isonicotinamide | N-[4-(5-chloro-2-thiophenyl)-2-thiazolyl]-4-pyridinecarboxamide | N-[4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-yl]pyridine-4-carboxamide | SMR000065040 | cid_2671470
Type:
Small organic molecule
Emp. Form.:
C13H8ClN3OS2
Mol. Mass.:
321.805
SMILES:
Clc1ccc(s1)-c1csc(NC(=O)c2ccncc2)n1
Structure:
Search PDB for entries with ligand similarity: