Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46344
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
4994±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46344
Synonyms:
MLS000087075 | N-(3-hydroxyphenyl)-5-(3-methoxyphenyl)-1,2-oxazole-3-carboxamide | N-(3-hydroxyphenyl)-5-(3-methoxyphenyl)-3-isoxazolecarboxamide | N-(3-hydroxyphenyl)-5-(3-methoxyphenyl)isoxazole-3-carboxamide | SMR000023298 | cid_3243797
Type:
Small organic molecule
Emp. Form.:
C17H14N2O4
Mol. Mass.:
310.3041
SMILES:
COc1cccc(c1)-c1cc(no1)C(=O)Nc1cccc(O)c1
Structure:
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