Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46352
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
3832±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46352
Synonyms:
MLS000118909 | N-cyclopropyl-4H-thieno[3,2-c][1]benzopyran-2-carboxamide | N-cyclopropyl-4H-thieno[3,2-c]chromene-2-carboxamide | SMR000095849 | cid_5308538
Type:
Small organic molecule
Emp. Form.:
C15H13NO2S
Mol. Mass.:
271.334
SMILES:
O=C(NC1CC1)c1cc2COc3ccccc3-c2s1
Structure:
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