Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46388
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
3466±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46388
Synonyms:
3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-fluorobenzyl)oxy]-2-methylquinoline | 3-[(4-fluorophenyl)methoxy]-2-methyl-quinoline | 3-[(4-fluorophenyl)methoxy]-2-methylquinoline | MLS000547371 | SMR000180270 | cid_3787931
Type:
Small organic molecule
Emp. Form.:
C17H14FNO
Mol. Mass.:
267.2976
SMILES:
Cc1nc2ccccc2cc1OCc1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: