Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46412
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
6113±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46412
Synonyms:
2-(2-naphthalenyloxy)-N-pyridin-4-ylacetamide | 2-(2-naphthoxy)-N-(4-pyridyl)acetamide | 2-naphthalen-2-yloxy-N-pyridin-4-yl-ethanamide | 2-naphthalen-2-yloxy-N-pyridin-4-ylacetamide | MLS000765153 | SMR000288558 | cid_823638
Type:
Small organic molecule
Emp. Form.:
C17H14N2O2
Mol. Mass.:
278.3053
SMILES:
O=C(COc1ccc2ccccc2c1)Nc1ccncc1
Structure:
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