Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46423
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
1610±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46423
Synonyms:
4-(4-benzylpiperidin-1-yl)thieno[2,3-d]pyrimidine | 4-(4-benzylpiperidino)thieno[2,3-d]pyrimidine | 4-[4-(phenylmethyl)-1-piperidinyl]thieno[2,3-d]pyrimidine | 4-[4-(phenylmethyl)piperidin-1-yl]thieno[2,3-d]pyrimidine | MLS001007458 | SMR000352660 | cid_2100018
Type:
Small organic molecule
Emp. Form.:
C18H19N3S
Mol. Mass.:
309.429
SMILES:
C(C1CCN(CC1)c1ncnc2sccc12)c1ccccc1
Structure:
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