Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46426
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
5217±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46426
Synonyms:
(3Z)-1-(4-benzoyl-1-pyridin-1-iumyl)-3-(1,3,3-trimethyl-2-indolylidene)-2-propanone;chloride | (3Z)-1-(4-benzoylpyridin-1-ium-1-yl)-3-(1,3,3-trimethylindol-2-ylidene)propan-2-one;chloride | (3Z)-1-(4-benzoylpyridin-1-ium-1-yl)-3-(1,3,3-trimethylindolin-2-ylidene)acetone;chloride | (3Z)-1-[4-(phenylcarbonyl)pyridin-1-ium-1-yl]-3-(1,3,3-trimethylindol-2-ylidene)propan-2-one;chloride | MLS000770890 | SMR000343999 | cid_16196204
Type:
Small organic molecule
Emp. Form.:
C26H25N2O2
Mol. Mass.:
397.4884
SMILES:
CN1C(=CC(=O)C[n+]2ccc(cc2)C(=O)c2ccccc2)C(C)(C)c2ccccc12 |w:3.3|
Structure:
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