Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31369
Substrate
n/a
Meas. Tech.
Dose response cell-based high throughput screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 3 (S1P3)
IC50
>50000±n/a nM
Citation
 PubChem, PC Dose response cell-based high throughput screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 3 (S1P3) PubChem Bioassay (2009)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31369
Synonyms:
1-Allyl-4-((4-chloro-phenyl)-{1-[2-(3,4-dimethoxy-phenyl)-ethyl]-1H-tetrazol-5-yl}-methyl)-piperazine | 1-[(4-chlorophenyl)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3,4-tetrazol-5-yl]methyl]-4-prop-2-enyl-piperazine;hydrochloride | 1-[(4-chlorophenyl)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-5-tetrazolyl]methyl]-4-prop-2-enylpiperazine;hydrochloride | 1-[(4-chlorophenyl)-[1-[2-(3,4-dimethoxyphenyl)ethyl]tetrazol-5-yl]methyl]-4-prop-2-enylpiperazine;hydrochloride | 1-allyl-4-[(4-chlorophenyl)-(1-homoveratryltetrazol-5-yl)methyl]piperazine;hydrochloride | MLS000880336 | SMR000005111 | cid_6603187
Type:
Small organic molecule
Emp. Form.:
C25H31ClN6O2
Mol. Mass.:
483.006
SMILES:
COc1ccc(CCn2nnnc2C(N2CCN(CC=C)CC2)c2ccc(Cl)cc2)cc1OC
Structure:
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