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Target
Mucolipin-3
Ligand
BDBM44578
Substrate
n/a
Meas. Tech.
Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)
EC50
>29900±n/a nM
Citation
 PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay (2009)[AID] 
Target
Name:
Mucolipin-3
Synonyms:
MCLN3_HUMAN | MCOLN3 | MCOLN3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64244.09
Organism:
Homo sapiens (Human)
Description:
Q8TDD5
Residue:
553
Sequence:
MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK
  
Inhibitor
Name:
BDBM44578
Synonyms:
1-(5-bromanylthiophen-2-yl)sulfonyl-4-methyl-piperidine | 1-(5-bromothiophen-2-yl)sulfonyl-4-methylpiperidine | 1-[(5-bromo-2-thienyl)sulfonyl]-4-methyl-piperidine | 1-[(5-bromo-2-thienyl)sulfonyl]-4-methylpiperidine | 1-[(5-bromo-2-thiophenyl)sulfonyl]-4-methylpiperidine | FLURANDRENOLIDE | MLS000069556 | MLS000099277 | SMR000058825 | SMR000073540 | cid_15209 | cid_893468
Type:
Small organic molecule
Emp. Form.:
C10H14BrNO2S2
Mol. Mass.:
324.258
SMILES:
CC1CCN(CC1)S(=O)(=O)c1ccc(Br)s1
Structure:
Search PDB for entries with ligand similarity: