Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46609
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46609
Synonyms:
1,3-bis(1H-1,2,4-triazol-5-ylsulfanyl)propan-2-one | 1,3-bis(1H-1,2,4-triazol-5-ylthio)-2-propanone | 1,3-bis(1H-1,2,4-triazol-5-ylthio)acetone | MLS-0238694.0001 | cid_1625367
Type:
Small organic molecule
Emp. Form.:
C7H8N6OS2
Mol. Mass.:
256.308
SMILES:
O=C(CSc1nnc[nH]1)CSc1nnc[nH]1
Structure:
Search PDB for entries with ligand similarity: