Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM35367
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM35367
Synonyms:
(6-methyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-yl)-phenyl-amine | 6-methyl-N-phenyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-amine | MLS000037067 | SMR000037024 | cid_5293709
Type:
Small organic molecule
Emp. Form.:
C11H12N4S
Mol. Mass.:
232.305
SMILES:
Cc1cc2NC(Nc3ccccc3)Sn2n1
Structure:
Search PDB for entries with ligand similarity: