Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM46044
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
824±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM46044
Synonyms:
3-(3-keto-1,2-benzothiazol-2-yl)benzoic acid methyl ester | 3-(3-oxo-1,2-benzothiazol-2-yl)benzoic acid methyl ester | MLS-0315861.0001 | cid_25067463 | methyl 3-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzoate | methyl 3-(3-oxo-1,2-benzothiazol-2-yl)benzoate
Type:
Small organic molecule
Emp. Form.:
C15H11NO3S
Mol. Mass.:
285.318
SMILES:
COC(=O)c1cccc(c1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: