Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM45071
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
29200±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM45071
Synonyms:
3-[4-[(Z)-(2-amino-4-keto-2-thiazolin-5-ylidene)methyl]-3-(4-chlorophenyl)pyrazol-1-yl]propionic acid | 3-[4-[(Z)-(2-amino-4-oxo-1,3-thiazol-5-ylidene)methyl]-3-(4-chlorophenyl)pyrazol-1-yl]propanoic acid | 3-[4-[(Z)-(2-amino-4-oxo-5-thiazolylidene)methyl]-3-(4-chlorophenyl)-1-pyrazolyl]propanoic acid | 3-[4-[(Z)-(2-azanyl-4-oxidanylidene-1,3-thiazol-5-ylidene)methyl]-3-(4-chlorophenyl)pyrazol-1-yl]propanoic acid | 3-{3-(4-chlorophenyl)-4-[(Z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]-1H-pyrazol-1-yl}propanoic acid | MLS000585888 | SMR000207669 | cid_12004457
Type:
Small organic molecule
Emp. Form.:
C16H13ClN4O3S
Mol. Mass.:
376.817
SMILES:
NC1=NC(=O)C(S1)=Cc1cn(CCC(O)=O)nc1-c1ccc(Cl)cc1 |w:7.8,t:1|
Structure:
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