Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47591
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
1512±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47591
Synonyms:
(6'-acetyloxy-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-3'-yl) ethanoate | (6'-acetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) acetate | MLS000722997 | SMR000236387 | acetic acid (6'-acetoxy-3-keto-spiro[phthalan-1,9'-xanthene]-3'-yl) ester | acetic acid (6'-acetyloxy-3-oxo-3'-spiro[isobenzofuran-1,9'-xanthene]yl) ester | cid_65047
Type:
Small organic molecule
Emp. Form.:
C24H16O7
Mol. Mass.:
416.3796
SMILES:
CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3ccccc23)c1
Structure:
Search PDB for entries with ligand similarity: