Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47608
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
53720±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47608
Synonyms:
(4E)-2-bromanyl-6-methoxy-4-[[(phenylmethyl)amino]-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | (4E)-2-bromo-4-[mercapto-[(phenylmethyl)amino]methylidene]-6-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[(benzylamino)-mercapto-methylene]-2-bromo-6-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-sulfanylmethylidene]-2-bromo-6-methoxycyclohexa-2,5-dien-1-one | MLS000663203 | N-benzyl-3-bromo-4-hydroxy-5-methoxybenzenecarbothioamide | SMR000301016 | cid_6096903
Type:
Small organic molecule
Emp. Form.:
C15H14BrNO2S
Mol. Mass.:
352.246
SMILES:
COc1cc(cc(Br)c1O)C(=S)NCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: