Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM2434
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
31250±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM2434
Synonyms:
6-benzyl-2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one | 6-benzyl-2-(methylthio)-1H-pyrimidin-4-one | S-DABO | thio-DABO 7a
Type:
Small organic molecule
Emp. Form.:
C12H12N2OS
Mol. Mass.:
232.301
SMILES:
CSc1nc(Cc2ccccc2)cc(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: