Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47662
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
6645±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47662
Synonyms:
MLS000622002 | N-cyclohexyl-2-[4-[(2-sulfanylidene-1H-quinazolin-4-yl)amino]phenyl]acetamide | N-cyclohexyl-2-[4-[(2-sulfanylidene-1H-quinazolin-4-yl)amino]phenyl]ethanamide | N-cyclohexyl-2-[4-[(2-thioxo-1H-quinazolin-4-yl)amino]phenyl]acetamide | N-cyclohexyl-2-{4-[(2-thioxo-1,2-dihydroquinazolin-4-yl)amino]phenyl}acetamide | SMR000310929 | cid_4121863
Type:
Small organic molecule
Emp. Form.:
C22H24N4OS
Mol. Mass.:
392.517
SMILES:
O=C(Cc1ccc(Nc2[nH]c(=S)nc3ccccc23)cc1)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: