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Target
Regulator of G-protein signaling 8
Ligand
BDBM47697
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47697
Synonyms:
MLS000071118 | SMR000003789 | [2-(2,3-dihydro-1H-inden-5-ylamino)-3-pyridinyl]-(4-morpholinyl)methanone | [2-(2,3-dihydro-1H-inden-5-ylamino)pyridin-3-yl]-morpholin-4-yl-methanone | [2-(2,3-dihydro-1H-inden-5-ylamino)pyridin-3-yl]-morpholin-4-ylmethanone | [2-(Indan-5-ylamino)-pyridin-3-yl]-morpholin-4-yl-methanone | [2-(indan-5-ylamino)-3-pyridyl]-morpholino-methanone | cid_651142
Type:
Small organic molecule
Emp. Form.:
C19H21N3O2
Mol. Mass.:
323.3889
SMILES:
O=C(N1CCOCC1)c1cccnc1Nc1ccc2CCCc2c1
Structure:
Search PDB for entries with ligand similarity: