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Target
Regulator of G-protein signaling 8
Ligand
BDBM47708
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47708
Synonyms:
1-(4-chlorobenzyl)sulfonylisonipecotic acid ethyl ester | 1-[(4-chlorophenyl)methylsulfonyl]-4-piperidinecarboxylic acid ethyl ester | MLS000066348 | SMR000081233 | cid_2228514 | ethyl 1-[(4-chlorobenzyl)sulfonyl]-4-piperidinecarboxylate | ethyl 1-[(4-chlorophenyl)methylsulfonyl]piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H20ClNO4S
Mol. Mass.:
345.842
SMILES:
CCOC(=O)C1CCN(CC1)S(=O)(=O)Cc1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: