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Target
Regulator of G-protein signaling 8
Ligand
BDBM47731
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47731
Synonyms:
MLS000583733 | N-(2-oxo-2-{[3-(trifluoromethyl)phenyl]amino}ethyl)benzamide (non-preferred name) | N-[2-keto-2-[3-(trifluoromethyl)anilino]ethyl]benzamide | N-[2-oxidanylidene-2-[[3-(trifluoromethyl)phenyl]amino]ethyl]benzamide | N-[2-oxo-2-[3-(trifluoromethyl)anilino]ethyl]benzamide | SMR000200754 | cid_1262361
Type:
Small organic molecule
Emp. Form.:
C16H13F3N2O2
Mol. Mass.:
322.2818
SMILES:
FC(F)(F)c1cccc(NC(=O)CNC(=O)c2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: